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BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment

Emerging evidence indicates B-cell activating factor (BAFF, Tnfsf13b) to be an important cytokine for antitumor immunity. In this study, we generated a BAFF-overexpressing B16.F10 melanoma cell model and found that BAFF-expressing tumors grow more slowly in vivo than control tumors. The tumor microe...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Stachura, Paweł, Xu, Haifeng C., Váraljai, Renáta, Shinde, Prashant, Ganesh, Nikkitha Umesh, Mack, Matthias, Van Lierop, Anke, Huang, Anfei, Sundaram, Balamurugan, Lang, Karl S., Picard, Daniel, Fischer, Ute, Remke, Marc, Homey, Bernhard, Roesch, Alexander, Häussinger, Dieter, Lang, Philipp A., Borkhardt, Arndt, Pandyra, Aleksandra A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397630/
https://www.ncbi.nlm.nih.gov/pubmed/34810198
http://dx.doi.org/10.1158/0008-5472.CAN-21-1171