Squalene in oil-based adjuvant improves the immunogenicity of SARS-CoV-2 RBD and confirms safety in animal models

COVID-19 pandemic has accelerated the development of vaccines against its etiologic agent, SARS-CoV-2. However, the emergence of new variants of the virus lead to the generation of new alternatives to improve the current sub-unit vaccines in development. In the present report, the immunogenicity of...

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Detalles Bibliográficos
Autores principales: Choque-Guevara, Ricardo, Poma-Acevedo, Astrid, Montesinos-Millán, Ricardo, Rios-Matos, Dora, Gutiérrez-Manchay, Kristel, Montalvan-Avalos, Angela, Quiñones-Garcia, Stefany, Cauti-Mendoza, Maria de Grecia, Agurto-Arteaga, Andres, Ramirez-Ortiz, Ingrid, Criollo-Orozco, Manuel, Huaccachi-Gonzales, Edison, Romero, Yomara K., Perez-Martinez, Norma, Isasi-Rivas, Gisela, Sernaque-Aguilar, Yacory, Villanueva-Pérez, Doris, Ygnacio, Freddy, Vallejos-Sánchez, Katherine, Fernández-Sánchez, Manolo, Guevara-Sarmiento, Luis A., Fernández-Díaz, Manolo, Zimic, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397949/
https://www.ncbi.nlm.nih.gov/pubmed/35998134
http://dx.doi.org/10.1371/journal.pone.0269823

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