Cargando…

Outer membrane vesicles of Porphyromonas gingivalis trigger NLRP3 inflammasome and induce neuroinflammation, tau phosphorylation, and memory dysfunction in mice

BACKGROUND: Porphyromonas gingivalis (Pg), the keystone pathogen in chronic periodontitis, is reported to initiate Alzheimer’s disease pathologies in preclinical studies. However, the specific mechanisms and signaling pathways acting on the brain still need to be further explored. Outer membrane ves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gong, Ting, Chen, Qi, Mao, Hongchen, Zhang, Yao, Ren, Huan, Xu, Mengmeng, Chen, Hong, Yang, Deqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397999/ https://www.ncbi.nlm.nih.gov/pubmed/36017373 http://dx.doi.org/10.3389/fcimb.2022.925435

Ejemplares similares

Bacterial growth stage determines the yields, protein composition, and periodontal pathogenicity of Porphyromonas gingivalis outer membrane vesicles
por: Mao, Hongchen, et al.
Publicado: (2023)

The Role of Porphyromonas gingivalis Outer Membrane Vesicles in Periodontal Disease and Related Systemic Diseases
por: Zhang, Zhiying, et al.
Publicado: (2021)

Porphyromonas gingivalis-Induced Cognitive Impairment Is Associated With Gut Dysbiosis, Neuroinflammation, and Glymphatic Dysfunction
por: Chi, Li, et al.
Publicado: (2021)

Interaction Between Autophagy and Porphyromonas gingivalis-Induced Inflammation
por: Kang, Sen, et al.
Publicado: (2022)

Periodontitis induced by Porphyromonas gingivalis drives impaired glucose metabolism in mice
por: Kang, Ni, et al.
Publicado: (2022)

The Relationship Between Porphyromonas Gingivalis and Rheumatoid Arthritis: A Meta-Analysis
por: Li, Yilin, et al.
Publicado: (2022)

The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromonas gingivalis
por: Ng, Hong Min, et al.
Publicado: (2019)

Porphyromonas gingivalis Induces Bisphosphonate-Related Osteonecrosis of the Femur in Mice
por: Wu, Shuxuan, et al.
Publicado: (2022)

Correlation Analysis of Gut Microbiota and Serum Metabolome With Porphyromonas gingivalis-Induced Metabolic Disorders
por: Dong, ZhengJie, et al.
Publicado: (2022)

Endotoxemia by Porphyromonas gingivalis Alters Endocrine Functions in Brown Adipose Tissue
por: Hatasa, Masahiro, et al.
Publicado: (2021)

Editorial: Porphyromonas gingivalis: molecular mechanisms of invasion, immune evasion, and dysbiosis
por: Chopra, Aditi, et al.
Publicado: (2023)

Host insulin resistance caused by Porphyromonas gingivalis-review of recent progresses
por: Jia, Shuxian, et al.
Publicado: (2023)

Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles
por: Fleetwood, Andrew J., et al.
Publicado: (2017)

Porphyromonas gingivalis Outer Membrane Vesicles Increase Vascular Permeability
por: Farrugia, C., et al.
Publicado: (2020)

Fimbriae-mediated outer membrane vesicle production and invasion of Porphyromonas gingivalis
por: Mantri, Chinmay K, et al.
Publicado: (2015)

Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors
por: Jia, Lu, et al.
Publicado: (2019)

PD-L1 Up-Regulation in Prostate Cancer Cells by Porphyromonas gingivalis
por: Groeger, Sabine, et al.
Publicado: (2022)

LL-37-Induced Autophagy Contributed to the Elimination of Live Porphyromonas gingivalis Internalized in Keratinocytes
por: Yang, Xue, et al.
Publicado: (2020)

Porphyromonas gingivalis Provokes Exosome Secretion and Paracrine Immune Senescence in Bystander Dendritic Cells
por: Elsayed, Ranya, et al.
Publicado: (2021)

Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids
por: Dahlstrand Rudin, Agnes, et al.
Publicado: (2021)

Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases
por: Chow, Yoke Chan, et al.
Publicado: (2022)

Association between Porphyromonas Gingivalis and systemic diseases: Focus on T cells-mediated adaptive immunity
por: Li, Cheng, et al.
Publicado: (2022)

Predictive value of the presence of Prevotella and the ratio of Porphyromonas gingivalis to Prevotella in saliva for esophageal squamous cell carcinoma
por: Chen, Xiaohui, et al.
Publicado: (2022)

Intracellular Porphyromonas gingivalis Promotes the Proliferation of Colorectal Cancer Cells via the MAPK/ERK Signaling Pathway
por: Mu, Wenxin, et al.
Publicado: (2020)

Outer membrane vesicles of Porphyromonas gingivalis: Novel communication tool and strategy
por: Okamura, Hirohiko, et al.
Publicado: (2021)

Role of Porphyromonas gingivalis outer membrane vesicles in oral mucosal transmission of HIV
por: Dong, Xin-Hong, et al.
Publicado: (2018)

TrkA serves as a virulence modulator in Porphyromonas gingivalis by maintaining heme acquisition and pathogenesis
por: Zou, Renjie, et al.
Publicado: (2022)

Sialidase facilitates Porphyromonas gingivalis immune evasion by reducing M1 polarization, antigen presentation, and phagocytosis of infected macrophages
por: Fan, Xiaomiao, et al.
Publicado: (2023)

Fast, Simple, and Highly Specific Molecular Detection of Porphyromonas gingivalis Using Isothermal Amplification and Lateral Flow Strip Methods
por: Ge, Duobao, et al.
Publicado: (2022)

Porphyromonas gingivalis PgFur Is a Member of a Novel Fur Subfamily With Non-canonical Function
por: Śmiga, Michał, et al.
Publicado: (2019)

Porphyromonas gingivalis secretion leads to dysplasia of normal esophageal epithelial cells via the Sonic hedgehog pathway
por: Jia, Xueting, et al.
Publicado: (2022)

Outer Membrane Vesicles of Porphyromonas gingivalis Elicit a Mucosal Immune Response
por: Nakao, Ryoma, et al.
Publicado: (2011)

Are Porphyromonas gingivalis Outer Membrane Vesicles Microbullets for Sporadic Alzheimer’s Disease Manifestation?
por: Singhrao, Sim K., et al.
Publicado: (2018)

Variability in Genomic and Virulent Properties of Porphyromonas gingivalis Strains Isolated From Healthy and Severe Chronic Periodontitis Individuals
por: Mendez, Katterinne N., et al.
Publicado: (2019)

A Uniquely Altered Oral Microbiome Composition Was Observed in Pregnant Rats With Porphyromonas gingivalis Induced Periodontal Disease
por: Walkenhorst, Molly S., et al.
Publicado: (2020)

Differential Response of Oral Mucosal and Gingival Cells to Corynebacterium durum, Streptococcus sanguinis, and Porphyromonas gingivalis Multispecies Biofilms
por: Redanz, Ulrike, et al.
Publicado: (2021)

Shut-Down of Type IX Protein Secretion Alters the Host Immune Response to Tannerella forsythia and Porphyromonas gingivalis
por: Braun, Matthias L., et al.
Publicado: (2022)

Zoledronic acid affects the process of Porphyromonas gingivalis infecting oral mucosal epithelial barrier: An in-vivo and in-vitro study
por: Sun, Hanyu, et al.
Publicado: (2023)

Functional Advantages of Porphyromonas gingivalis Vesicles
por: Ho, Meng-Hsuan, et al.
Publicado: (2015)

Porphyromonas gingivalis-Induced Neuroinflammation in Alzheimer’s Disease
por: Olsen, Ingar
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_g7su6luhkfuem1ui5pv4gp6psp