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Castration-Induced Downregulation of SPARC in Stromal Cells Drives Neuroendocrine Differentiation of Prostate Cancer

Fatal neuroendocrine differentiation (NED) of castration-resistant prostate cancer is a recurrent mechanism of resistance to androgen deprivation therapies (ADT) and antiandrogen receptor pathway inhibitors (ARPI) in patients. The design of effective therapies for neuroendocrine prostate cancer (NEP...

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Detalles Bibliográficos
Autores principales:	Enriquez, Claudia, Cancila, Valeria, Ferri, Renata, Sulsenti, Roberta, Fischetti, Irene, Milani, Matteo, Ostano, Paola, Gregnanin, Ilaria, Mello-Grand, Maurizia, Berrino, Enrico, Bregni, Marco, Renne, Giuseppe, Tripodo, Claudio, Colombo, Mario P., Jachetti, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2021
Materias:	Tumor Biology and Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398117/ https://www.ncbi.nlm.nih.gov/pubmed/34185677 http://dx.doi.org/10.1158/0008-5472.CAN-21-0163

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