Substrate-inducible and antibiotic-free high-level 4-hydroxyvaleric acid production in engineered Escherichia coli

In this study, we developed a levulinic acid (LA)-inducible and antibiotic-free plasmid system mediated by HpdR/P( hpdH ) and infA-complementation to produce 4-hydroxyvaleric acid (4-HV) from LA in an engineered Escherichia coli strain. The system was efficiently induced by the addition of the LA su...

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Detalles Bibliográficos
Autores principales: Sathesh-Prabu, Chandran, Tiwari, Rameshwar, Lee, Sung Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398171/
https://www.ncbi.nlm.nih.gov/pubmed/36017349
http://dx.doi.org/10.3389/fbioe.2022.960907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398171/
https://www.ncbi.nlm.nih.gov/pubmed/36017349
http://dx.doi.org/10.3389/fbioe.2022.960907

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