Clonal Hematopoiesis Before, During, and After Human Spaceflight

Clonal hematopoiesis (CH) occurs when blood cells harboring an advantageous mutation propagate faster than others. These mutations confer a risk for hematological cancers and cardiovascular disease. Here, we analyze CH in blood samples from a pair of twin astronauts over 4 years in bulk and fraction...

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Detalles Bibliográficos
Autores principales: Mencia-Trinchant, Nuria, MacKay, Matthew J., Chin, Christopher, Afshinnekoo, Ebrahim, Foox, Jonathan, Meydan, Cem, Butler, Daniel, Mozsary, Christopher, Vernice, Nicholas A., Darby, Charlotte, Schatz, Michael C., Bailey, Susan M., Melnick, Ari M., Guzman, Monica L., Bolton, Kelly, Braunstein, Lior Z., Garrett-Bakelman, Francine, Levine, Ross L., Hassane, Duane C., Mason, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398182/
https://www.ncbi.nlm.nih.gov/pubmed/33242405
http://dx.doi.org/10.1016/j.celrep.2020.108458

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