Cargando…
How splicing confers treatment resistance in prostate cancer
A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside.
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398401/ https://www.ncbi.nlm.nih.gov/pubmed/35998026 http://dx.doi.org/10.7554/eLife.82070 |
| _version_ | 1784772320593707008 |
|---|---|
| author | Konda, Prathyusha Viswanathan, Srinivas R |
| author_facet | Konda, Prathyusha Viswanathan, Srinivas R |
| author_sort | Konda, Prathyusha |
| collection | PubMed |
| description | A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside. |
| format | Online Article Text |
| id | pubmed-9398401 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | eLife Sciences Publications, Ltd |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-93984012022-08-24 How splicing confers treatment resistance in prostate cancer Konda, Prathyusha Viswanathan, Srinivas R eLife Cancer Biology A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside. eLife Sciences Publications, Ltd 2022-08-23 /pmc/articles/PMC9398401/ /pubmed/35998026 http://dx.doi.org/10.7554/eLife.82070 Text en © 2022, Konda and Viswanathan https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
| spellingShingle | Cancer Biology Konda, Prathyusha Viswanathan, Srinivas R How splicing confers treatment resistance in prostate cancer |
| title | How splicing confers treatment resistance in prostate cancer |
| title_full | How splicing confers treatment resistance in prostate cancer |
| title_fullStr | How splicing confers treatment resistance in prostate cancer |
| title_full_unstemmed | How splicing confers treatment resistance in prostate cancer |
| title_short | How splicing confers treatment resistance in prostate cancer |
| title_sort | how splicing confers treatment resistance in prostate cancer |
| topic | Cancer Biology |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398401/ https://www.ncbi.nlm.nih.gov/pubmed/35998026 http://dx.doi.org/10.7554/eLife.82070 |
| work_keys_str_mv | AT kondaprathyusha howsplicingconferstreatmentresistanceinprostatecancer AT viswanathansrinivasr howsplicingconferstreatmentresistanceinprostatecancer |