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How splicing confers treatment resistance in prostate cancer

A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside.

Detalles Bibliográficos
Autores principales:	Konda, Prathyusha, Viswanathan, Srinivas R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398401/ https://www.ncbi.nlm.nih.gov/pubmed/35998026 http://dx.doi.org/10.7554/eLife.82070

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