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Isolation and characterization of human anti-CD20 single-chain variable fragment (scFv) from a Naive human scFv library
CD20 is a receptor expressed on B cells with anonymous functions. The receptor is the target of some food and drug administration (FDA) approved monoclonal antibodies (mAb), such as Rituximab and Obinutuzumab. Blocking CD20 using the aforementioned mAbs has improved Non-Hodgkin Lymphoma (NHL) therap...
Autores principales: | Shams, Nasir, Khoshtinat Nikkhoi, Shahryar, Gu, Zhanjun, Rahbarizadeh, Fatemeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398497/ https://www.ncbi.nlm.nih.gov/pubmed/35999405 http://dx.doi.org/10.1007/s12032-022-01757-1 |
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