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Isolation and characterization of human anti-CD20 single-chain variable fragment (scFv) from a Naive human scFv library

CD20 is a receptor expressed on B cells with anonymous functions. The receptor is the target of some food and drug administration (FDA) approved monoclonal antibodies (mAb), such as Rituximab and Obinutuzumab. Blocking CD20 using the aforementioned mAbs has improved Non-Hodgkin Lymphoma (NHL) therap...

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Detalles Bibliográficos
Autores principales: Shams, Nasir, Khoshtinat Nikkhoi, Shahryar, Gu, Zhanjun, Rahbarizadeh, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398497/
https://www.ncbi.nlm.nih.gov/pubmed/35999405
http://dx.doi.org/10.1007/s12032-022-01757-1

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