Cargando…
TAK-242 Ameliorates Hepatic Fibrosis by Regulating the Liver-Gut Axis
OBJECTIVE: The aims of this study were to investigate the impact of TAK-242 on the Toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88)/nuclear transcription factor-κB (NF-κB) signal transduction pathway in rats with hepatic fibrosis (HF) using the liver gut axis and to investigate...
Autores principales: | Liu, Sujie, Wu, Juan, Chen, Pingping, Mohammed, Shadi A. D., Zhang, Jingbo, Liu, Shumin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398794/ https://www.ncbi.nlm.nih.gov/pubmed/36017390 http://dx.doi.org/10.1155/2022/4949148 |
Ejemplares similares
-
Exploration of the potential mechanism of Baicalin for hepatic fibrosis based on network pharmacology, gut microbiota, and experimental validation
por: Liu, Sujie, et al.
Publicado: (2023) -
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats
por: Zhong, Xiang, et al.
Publicado: (2019) -
TAK-242 ameliorates DSS-induced colitis by regulating the gut microbiota and the JAK2/STAT3 signaling pathway
por: Wang, Jiajia, et al.
Publicado: (2020) -
TAK-242 ameliorates contact dermatitis exacerbated by IL-36 receptor antagonist deficiency
por: Fukushima, Hidehiko, et al.
Publicado: (2020) -
TAK-242 ameliorates epileptic symptoms in mice by inhibiting the TLR4/NF-κB signaling pathway
por: Dong, Jibo, et al.
Publicado: (2022)