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Ligustilide Improves Cognitive Impairment via Regulating the SIRT1/IRE1α/XBP1s/CHOP Pathway in Vascular Dementia Rats

Vascular dementia (VaD), the second cause of dementia, is caused by chronic cerebral hypoperfusion, producing progressive damage to cerebral cortex, hippocampus, and white matter. Ligustilide (LIG), one of the main active ingredients of Angelica sinensis, exerts the neuroprotective effect on neurode...

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Detalles Bibliográficos
Autores principales:	Peng, Dong, Wang, Yi-Xue, Huang, Tian-Hua, Luo, Dan, Qiao, Li-Jun, Wang, Qi, Guan, Li, Cai, Ye-Feng, Zhang, Shi-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398841/ https://www.ncbi.nlm.nih.gov/pubmed/36017237 http://dx.doi.org/10.1155/2022/6664990

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