BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH

The role of hepatic cell senescence in human non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is not well understood. To examine this, we performed liver biopsies and extensive characterization of 58 individuals with or without NAFLD/NASH. Here, we show that hepatic...

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Detalles Bibliográficos
Autores principales: Baboota, Ritesh K., Rawshani, Aidin, Bonnet, Laurianne, Li, Xiangyu, Yang, Hong, Mardinoglu, Adil, Tchkonia, Tamar, Kirkland, James L., Hoffmann, Anne, Dietrich, Arne, Boucher, Jeremie, Blüher, Matthias, Smith, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398907/
https://www.ncbi.nlm.nih.gov/pubmed/35995996
http://dx.doi.org/10.1038/s42255-022-00620-x

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