Fullerenes for the treatment of cancer: an emerging tool

Cancer is a most common cause of mortality globally. Available medicines possess severe side effects owing to their non-specific targeting. Hence, there is a need of an alternative in the healthcare system that should have high efficacy with the least side effects, also having the ability to achieve...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandes, Neha Benedicta, Shenoy, Raghavendra Udaya Kumar, Kajampady, Mandira Kashi, DCruz, Cleona E. M., Shirodkar, Rupesh K., Kumar, Lalit, Verma, Ruchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399030/
https://www.ncbi.nlm.nih.gov/pubmed/35790637
http://dx.doi.org/10.1007/s11356-022-21449-7
Descripción
Sumario:Cancer is a most common cause of mortality globally. Available medicines possess severe side effects owing to their non-specific targeting. Hence, there is a need of an alternative in the healthcare system that should have high efficacy with the least side effects, also having the ability to achieve site-specific targeting and be reproducible. This is possible with the help of fullerenes. Fullerenes are having the unique physicochemical and photosensitizer properties. This article discusses the synthesis, functionalization, mechanism, various properties, and applications of C60 fullerenes in the treatment of cancer. The review article also addresses the various factors influencing the activity of fullerenes including the environmental conditions, toxicity profile, and future prospective. GRAPHICAL ABSTRACT: [Image: see text]

Ejemplares similares