Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy

PURPOSE: Fibroblast activation protein (FAP) is a membrane-bound protease that has limited expression in normal adult tissues but is highly expressed in the tumor microenvironment of many solid cancers. FAP-2286 is a FAP-binding peptide coupled to a radionuclide chelator that is currently being inve...

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Detalles Bibliográficos
Autores principales: Zboralski, Dirk, Hoehne, Aileen, Bredenbeck, Anne, Schumann, Anne, Nguyen, Minh, Schneider, Eberhard, Ungewiss, Jan, Paschke, Matthias, Haase, Christian, von Hacht, Jan L., Kwan, Tanya, Lin, Kevin K., Lenore, Jan, Harding, Thomas C., Xiao, Jim, Simmons, Andrew D., Mohan, Ajay-Mohan, Beindorff, Nicola, Reineke, Ulrich, Smerling, Christiane, Osterkamp, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399058/
https://www.ncbi.nlm.nih.gov/pubmed/35608703
http://dx.doi.org/10.1007/s00259-022-05842-5

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