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scRNA-seq of gastric tumor shows complex intercellular interaction with an alternative T cell exhaustion trajectory

The tumor microenvironment (TME) in gastric cancer (GC) has been shown to be important for tumor control but the specific characteristics for GC are not fully appreciated. We generated an atlas of 166,533 cells from 10 GC patients with matched paratumor tissues and blood. Our results show tumor-asso...

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Detalles Bibliográficos
Autores principales: Sun, Keyong, Xu, Runda, Ma, Fuhai, Yang, Naixue, Li, Yang, Sun, Xiaofeng, Jin, Peng, Kang, Wenzhe, Jia, Lemei, Xiong, Jianping, Hu, Haitao, Tian, Yantao, Lan, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399107/
https://www.ncbi.nlm.nih.gov/pubmed/35999201
http://dx.doi.org/10.1038/s41467-022-32627-z