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Genetically predicted telomere length and its relationship with neurodegenerative diseases and life expectancy

Telomere length (TL) is a biomarker of biological aging. Shorter telomeres have been associated with mortality and increased rates of age-related diseases. However, observational studies are unable to conclude whether TL is causally associated with those outcomes. Mendelian randomization (MR) was de...

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Detalles Bibliográficos
Autores principales: Rodríguez-Fernández, Blanca, Gispert, Juan Domingo, Guigo, Roderic, Navarro, Arcadi, Vilor-Tejedor, Natalia, Crous-Bou, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399257/
https://www.ncbi.nlm.nih.gov/pubmed/36051868
http://dx.doi.org/10.1016/j.csbj.2022.08.006

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