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Design, synthesis and biological evaluation of erlotinib-based IDO1 inhibitors

Erlotinib is a highly specific and reversible epidermal growth factor receptor tyrosine kinase inhibitor for the targeted therapy of non-small-cell lung cancer (NSCLC) However, the efficacy of erlotinib is limited because the development of drug resistance during chemotherapy. Indoleamine 2,3-dioxyg...

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Detalles Bibliográficos
Autores principales:	Hou, Xi-xi, Gong, Xiao-qing, Mao, Long-fei, Sun, Ge, Yang, Jian-xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399373/ https://www.ncbi.nlm.nih.gov/pubmed/36034879 http://dx.doi.org/10.3389/fphar.2022.940704

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