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High-throughput bioengineering of homogenous and functional human-induced pluripotent stem cells-derived liver organoids via micropatterning technique

Human pluripotent stem cell-derived liver organoids are emerging as more human-relevant in vitro models for studying liver diseases and hepatotoxicity than traditional hepatocyte cultures and animal models. The generation of liver organoids is based on the Matrigel dome method. However, the organoid...

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Detalles Bibliográficos
Autores principales: Xu, Xiaodong, Jiang, Shanqing, Gu, Longjun, Li, Bin, Xu, Fang, Li, Changyong, Chen, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399390/
https://www.ncbi.nlm.nih.gov/pubmed/36032707
http://dx.doi.org/10.3389/fbioe.2022.937595