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Deep learning approaches for conformational flexibility and switching properties in protein design

Following the hugely successful application of deep learning methods to protein structure prediction, an increasing number of design methods seek to leverage generative models to design proteins with improved functionality over native proteins or novel structure and function. The inherent flexibilit...

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Detalles Bibliográficos
Autores principales: Rudden, Lucas S. P., Hijazi, Mahdi, Barth, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399439/
https://www.ncbi.nlm.nih.gov/pubmed/36032687
http://dx.doi.org/10.3389/fmolb.2022.928534

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