SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature

Endoscopic retrograde cholangiopancreatography (ERCP) and biliary stent placement are standard palliative care procedures for patients with unresectable cholangiocarcinoma. However, the bile duct mucosa cannot be observed directly during the placement of a light diffuser in photodynamic therapy (PDT...

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Autores principales: Zhou, Jiangjiao, Xiong, Li, Liu, Wei, Liu, Chun, He, Chao, Zou, Heng, Wen, Yu, Lin, Liangwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399461/
https://www.ncbi.nlm.nih.gov/pubmed/36033447
http://dx.doi.org/10.3389/fonc.2022.890735
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author Zhou, Jiangjiao
Xiong, Li
Liu, Wei
Liu, Chun
He, Chao
Zou, Heng
Wen, Yu
Lin, Liangwu
author_facet Zhou, Jiangjiao
Xiong, Li
Liu, Wei
Liu, Chun
He, Chao
Zou, Heng
Wen, Yu
Lin, Liangwu
author_sort Zhou, Jiangjiao
collection PubMed
description Endoscopic retrograde cholangiopancreatography (ERCP) and biliary stent placement are standard palliative care procedures for patients with unresectable cholangiocarcinoma. However, the bile duct mucosa cannot be observed directly during the placement of a light diffuser in photodynamic therapy (PDT) and biopsy. SpyGlass can solve the above two problems. In this paper, we report the case of a patient who presented with obstructive jaundice and underwent endobiliary stenting placement several times. However, cholangiocarcinoma hyperplasia still led to stent blockage. We applied SpyGlass to guide the accurate placement of a light diffuser and evaluated the tumor necrosis after PDT. Results revealed the good application effect of this device.
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spelling pubmed-93994612022-08-25 SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature Zhou, Jiangjiao Xiong, Li Liu, Wei Liu, Chun He, Chao Zou, Heng Wen, Yu Lin, Liangwu Front Oncol Oncology Endoscopic retrograde cholangiopancreatography (ERCP) and biliary stent placement are standard palliative care procedures for patients with unresectable cholangiocarcinoma. However, the bile duct mucosa cannot be observed directly during the placement of a light diffuser in photodynamic therapy (PDT) and biopsy. SpyGlass can solve the above two problems. In this paper, we report the case of a patient who presented with obstructive jaundice and underwent endobiliary stenting placement several times. However, cholangiocarcinoma hyperplasia still led to stent blockage. We applied SpyGlass to guide the accurate placement of a light diffuser and evaluated the tumor necrosis after PDT. Results revealed the good application effect of this device. Frontiers Media S.A. 2022-08-10 /pmc/articles/PMC9399461/ /pubmed/36033447 http://dx.doi.org/10.3389/fonc.2022.890735 Text en Copyright © 2022 Zhou, Xiong, Liu, Liu, He, Zou, Wen and Lin https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Zhou, Jiangjiao
Xiong, Li
Liu, Wei
Liu, Chun
He, Chao
Zou, Heng
Wen, Yu
Lin, Liangwu
SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature
title SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature
title_full SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature
title_fullStr SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature
title_full_unstemmed SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature
title_short SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature
title_sort spyglass-guided photodynamic therapy for unresectable cholangiocarcinoma: a case report and review of the literature
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399461/
https://www.ncbi.nlm.nih.gov/pubmed/36033447
http://dx.doi.org/10.3389/fonc.2022.890735
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