Hepatic p53 is regulated by transcription factor FOXO1 and acutely controls glycogen homeostasis

The tumor suppressor p53 is involved in the adaptation of hepatic metabolism to nutrient availability. Acute deletion of p53 in the mouse liver affects hepatic glucose and triglyceride metabolism. However, long-term adaptations upon the loss of hepatic p53 and its transcriptional regulators are unkn...

Descripción completa

Detalles Bibliográficos
Autores principales: Oster, Moritz, Galhuber, Markus, Krstic, Jelena, Steinhoff, Julia S., Lenihan-Geels, Georgia, Wulff, Sascha, Kiefer, Marie F., Petricek, Konstantin M., Wowro, Sylvia J., Flores, Roberto E., Yang, Na, Li, Chen, Meng, Yueming, Reinisch, Isabel, Sommerfeld, Manuela, Weger, Stefan, Habisch, Hansjörg, Madl, Tobias, Schulz, Tim J., Prokesch, Andreas, Schupp, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399478/
https://www.ncbi.nlm.nih.gov/pubmed/35868560
http://dx.doi.org/10.1016/j.jbc.2022.102287

Ejemplares similares

Ejemplares similares