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Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE

Glioma stem cells (GSCs) in the hypoxic niches contribute to tumor initiation, progression, and recurrence in glioblastoma (GBM). Hypoxia induces release of high-mobility group box 1 (HMGB1) from tumor cells, promoting the development of tumor. Here, we report that HMGB1 is overexpressed in human GB...

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Detalles Bibliográficos
Autores principales:	Ye, Cuifang, Li, Huan, Li, Yachao, Zhang, Yang, Liu, Guohao, Mi, Hailong, Li, Honglian, Xiao, Qungen, Niu, Li, Yu, Xingjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399482/ https://www.ncbi.nlm.nih.gov/pubmed/36034219 http://dx.doi.org/10.1016/j.isci.2022.104872

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