The modulation of ion channels in cancer chemo-resistance

Ion channels modulate the flow of ions into and out of a cell or intracellular organelle, leading to generation of electrical or chemical signals and regulating ion homeostasis. The abundance of ion channels in the plasma and intracellular membranes are subject to physiological and pathological regu...

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Detalles Bibliográficos
Autores principales: Zhao, Jiayu, Li, Mei, Xu, Jiao, Cheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399684/
https://www.ncbi.nlm.nih.gov/pubmed/36033489
http://dx.doi.org/10.3389/fonc.2022.945896
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author Zhao, Jiayu
Li, Mei
Xu, Jiao
Cheng, Wei
author_facet Zhao, Jiayu
Li, Mei
Xu, Jiao
Cheng, Wei
author_sort Zhao, Jiayu
collection PubMed
description Ion channels modulate the flow of ions into and out of a cell or intracellular organelle, leading to generation of electrical or chemical signals and regulating ion homeostasis. The abundance of ion channels in the plasma and intracellular membranes are subject to physiological and pathological regulations. Abnormal and dysregulated expressions of many ion channels are found to be linked to cancer and cancer chemo-resistance. Here, we will summarize ion channels distribution in multiple tumors. And the involvement of ion channels in cancer chemo-resistance will be highlighted.
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spelling pubmed-93996842022-08-25 The modulation of ion channels in cancer chemo-resistance Zhao, Jiayu Li, Mei Xu, Jiao Cheng, Wei Front Oncol Oncology Ion channels modulate the flow of ions into and out of a cell or intracellular organelle, leading to generation of electrical or chemical signals and regulating ion homeostasis. The abundance of ion channels in the plasma and intracellular membranes are subject to physiological and pathological regulations. Abnormal and dysregulated expressions of many ion channels are found to be linked to cancer and cancer chemo-resistance. Here, we will summarize ion channels distribution in multiple tumors. And the involvement of ion channels in cancer chemo-resistance will be highlighted. Frontiers Media S.A. 2022-08-10 /pmc/articles/PMC9399684/ /pubmed/36033489 http://dx.doi.org/10.3389/fonc.2022.945896 Text en Copyright © 2022 Zhao, Li, Xu and Cheng https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Zhao, Jiayu
Li, Mei
Xu, Jiao
Cheng, Wei
The modulation of ion channels in cancer chemo-resistance
title The modulation of ion channels in cancer chemo-resistance
title_full The modulation of ion channels in cancer chemo-resistance
title_fullStr The modulation of ion channels in cancer chemo-resistance
title_full_unstemmed The modulation of ion channels in cancer chemo-resistance
title_short The modulation of ion channels in cancer chemo-resistance
title_sort modulation of ion channels in cancer chemo-resistance
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399684/
https://www.ncbi.nlm.nih.gov/pubmed/36033489
http://dx.doi.org/10.3389/fonc.2022.945896
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