β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells

Melanoma is a highly aggressive skin cancer and accounts for most of the skin cancer-related deaths. The efficacy of current therapies for melanoma remains to be improved. The isopropanolamine derivative of β-elemene LXX-8250 was reported to present better water solubility and stronger toxicity to t...

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Detalles Bibliográficos
Autores principales: Jalal, Sajid, Zhang, Ting, Deng, Jia, Wang, Jie, Xu, Ting, Zhang, Tianhua, Zhai, Chuanxin, Yuan, Ruqiang, Teng, Hongming, Huang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399853/
https://www.ncbi.nlm.nih.gov/pubmed/36034839
http://dx.doi.org/10.3389/fphar.2022.900973

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