Network metrics, structural dynamics and density functional theory calculations identified a novel Ursodeoxycholic Acid derivative against therapeutic target Parkin for Parkinson's disease

Parkinson's disease (PD) has been designated as one of the priority neurodegenerative disorders worldwide. Although diagnostic biomarkers have been identified, early onset detection and targeted therapy are still limited. An integrated systems and structural biology approach were adopted to ide...

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Detalles Bibliográficos
Autores principales: Naha, Aniket, Banerjee, Sanjukta, Debroy, Reetika, Basu, Soumya, Ashok, Gayathri, Priyamvada, P., Kumar, Hithesh, Preethi, A.R., Singh, Harpreet, Anbarasu, Anand, Ramaiah, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399899/
https://www.ncbi.nlm.nih.gov/pubmed/36051887
http://dx.doi.org/10.1016/j.csbj.2022.08.017

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