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Locally delivered antistaphylococcal lysin exebacase or CF-296 is active in methicillin-resistant Staphylococcus aureus implant-associated osteomyelitis
Introduction: Staphylococcus aureus is the most common cause of orthopedic infections and can be challenging to treat, especially in the presence of a foreign body. The antistaphylococcal lysins exebacase and CF-296 have rapid bactericidal activity, a low propensity for resistance development, and s...
Autores principales: | Karau, Melissa, Schmidt-Malan, Suzannah, Mandrekar, Jay, Lehoux, Dario, Schuch, Raymond, Cassino, Cara, Patel, Robin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Copernicus GmbH
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399932/ https://www.ncbi.nlm.nih.gov/pubmed/36032801 http://dx.doi.org/10.5194/jbji-7-169-2022 |
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