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Implications of NKG2A in immunity and immune-mediated diseases
In recent studies, NKG2A is revealed to be a key immune checkpoint for both natural killer (NK) cells and CD8(+) T cells. It form heterodimer receptors with CD94, and targets the peptide-presenting human leukocyte antigen-E (HLA-E) molecules. Upon crosslinking, NKG2A/CD94 delivers inhibitory signals...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399941/ https://www.ncbi.nlm.nih.gov/pubmed/36032104 http://dx.doi.org/10.3389/fimmu.2022.960852 |