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Implications of NKG2A in immunity and immune-mediated diseases

In recent studies, NKG2A is revealed to be a key immune checkpoint for both natural killer (NK) cells and CD8(+) T cells. It form heterodimer receptors with CD94, and targets the peptide-presenting human leukocyte antigen-E (HLA-E) molecules. Upon crosslinking, NKG2A/CD94 delivers inhibitory signals...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaotong, Xiong, Huabao, Ning, Zhaochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399941/ https://www.ncbi.nlm.nih.gov/pubmed/36032104 http://dx.doi.org/10.3389/fimmu.2022.960852

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