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Increased intrathecal neurofilament light and immunoglobulin M predict severe disability in relapsing-remitting multiple sclerosis

BACKGROUND: Emerging evidence supports that determination of intrathecal immunoglobulin M (IgM) synthesis (ITMS) and neurofilament light (NfL) concentration in cerebrospinal fluid (CSF) may be clinically useful as disease severity biomarkers in relapsing-remitting multiple sclerosis (RRMS). METHODS:...

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Detalles Bibliográficos
Autores principales:	Rosenstein, Igal, Rasch, Sofia, Axelsson, Markus, Novakova, Lenka, Blennow, Kaj, Zetterberg, Henrik, Lycke, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399944/ https://www.ncbi.nlm.nih.gov/pubmed/36032114 http://dx.doi.org/10.3389/fimmu.2022.967953

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