GPC3-targeted CAR-T cells secreting B7H3-targeted BiTE exhibit potent cytotoxicity activity against hepatocellular carcinoma cell in the in vitro assay

Hepatocellular carcinoma (HCC), the most common primary liver cancer has a high mortality in China, and it is usually diagnosed at a late stage, thereby leaving patients with few effective treatment options. Chimeric antigen receptor-T (CAR-T) cell therapy, a novel immunotherapy that has shown promi...

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Detalles Bibliográficos
Autores principales: Cao, Guozheng, Zhang, Guizhong, Liu, Maoxuan, Liu, Junchen, Wang, Qi, Zhu, Lifang, Wan, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399963/
https://www.ncbi.nlm.nih.gov/pubmed/36032401
http://dx.doi.org/10.1016/j.bbrep.2022.101324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399963/
https://www.ncbi.nlm.nih.gov/pubmed/36032401
http://dx.doi.org/10.1016/j.bbrep.2022.101324

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