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GPC3-targeted CAR-T cells secreting B7H3-targeted BiTE exhibit potent cytotoxicity activity against hepatocellular carcinoma cell in the in vitro assay

Hepatocellular carcinoma (HCC), the most common primary liver cancer has a high mortality in China, and it is usually diagnosed at a late stage, thereby leaving patients with few effective treatment options. Chimeric antigen receptor-T (CAR-T) cell therapy, a novel immunotherapy that has shown promi...

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Detalles Bibliográficos
Autores principales:	Cao, Guozheng, Zhang, Guizhong, Liu, Maoxuan, Liu, Junchen, Wang, Qi, Zhu, Lifang, Wan, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399963/ https://www.ncbi.nlm.nih.gov/pubmed/36032401 http://dx.doi.org/10.1016/j.bbrep.2022.101324

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