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Improving Transcriptome Fidelity Following Synovial Tissue Disaggregation
OBJECTIVE: To improve the fidelity of the cellular transcriptome of disaggregated synovial tissue for applications such as single-cell RNA sequencing (scRNAseq) by modifying the disaggregation technique. METHODS: Osteoarthritis (OA) and rheumatoid arthritis (RA) synovia were collected at arthroplast...
Autores principales: | Boyle, David L., Prideaux, Edward B., Hillman, Joshua, Wang, Wei, Firestein, Gary S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400013/ https://www.ncbi.nlm.nih.gov/pubmed/36035425 http://dx.doi.org/10.3389/fmed.2022.919748 |
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