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Development of RAG2 (-/-) IL2Rγ (-/Y) immune deficient FAH-knockout miniature pig

Human hepatocyte transplantation for liver disease treatment have been hampered by the lack of quality human hepatocytes. Pigs with their large body size, longevity and physiological similarities with human are appropriate animal models for the in vivo expansion of human hepatocytes. Here we report...

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Detalles Bibliográficos
Autores principales:	Zhao, Heng, Ye, Weijian, Guo, Jianxiong, Wang, Jiaoxiang, Jiao, Deling, Xu, Kaixiang, Yang, Chang, Chen, Shuhan, Jamal, Muhammad Ameen, Bai, Zhongbin, Wei, Taiyun, Cai, Jie, Nguyen, Tien Dat, Qing, Yubo, Cheng, Wenmin, Jia, Baoyu, Li, Honghui, Zhao, Hong-Ye, Chen, Qingfeng, Wei, Hong-Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400017/ https://www.ncbi.nlm.nih.gov/pubmed/36032112 http://dx.doi.org/10.3389/fimmu.2022.950194

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