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Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration

Malaria and other apicomplexan-caused diseases affect millions of humans, agricultural animals, and pets. Cell traversal is a common feature used by multiple apicomplexan parasites to migrate through host cells and can be exploited to develop therapeutics against these deadly parasites. Here, we pro...

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Detalles Bibliográficos
Autores principales: Kumar, Hirdesh, Jimah, John R., Misal, Santosh A., Salinas, Nichole D., Fried, Michal, Schlesinger, Paul H., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400078/
https://www.ncbi.nlm.nih.gov/pubmed/35809642
http://dx.doi.org/10.1016/j.jbc.2022.102241