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Efficacy of SCF drug conjugate targeting c-KIT in gastrointestinal stromal tumor

BACKGROUND: Gastrointestinal stromal tumor (GIST) is a rare type of cancer that occurs in the gastrointestinal tract. The majority of GIST cases carry oncogenic forms of KIT, the receptor for stem cell factor (SCF). Small molecule kinase inhibitor imatinib is effective in prolonging the survival of...

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Detalles Bibliográficos
Autores principales:	Zhang, Dengyang, He, Chunxiao, Guo, Yao, Li, Jianfeng, Li, Bo, Zhao, Yuming, Yu, Liuting, Chang, Zhiguang, Pei, Hanzhong, Yang, Ming, Li, Na, Zhang, Qi, He, Yulong, Pan, Yihang, Zhao, Zhizhuang Joe, Zhang, Changhua, Chen, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400206/ https://www.ncbi.nlm.nih.gov/pubmed/35999600 http://dx.doi.org/10.1186/s12916-022-02465-3

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