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Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study

BACKGROUND: This study investigated the impact of coronary angiography on outcomes of emergency operation in acute type A aortic dissection (ATAAD) patients who were initially misdiagnosed as an acute coronary syndrome. METHODS: From October 2016 to April 2019, 129 patients underwent emergency opera...

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Autores principales: Peng, Hao, Liu, Wei, Jian, Kai-Tao, Xia, Yu, Liu, Jian-Shi, Sun, Li-Zhong, Mei, Yun-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400216/
https://www.ncbi.nlm.nih.gov/pubmed/36002794
http://dx.doi.org/10.1186/s12872-022-02821-4
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author Peng, Hao
Liu, Wei
Jian, Kai-Tao
Xia, Yu
Liu, Jian-Shi
Sun, Li-Zhong
Mei, Yun-Qing
author_facet Peng, Hao
Liu, Wei
Jian, Kai-Tao
Xia, Yu
Liu, Jian-Shi
Sun, Li-Zhong
Mei, Yun-Qing
author_sort Peng, Hao
collection PubMed
description BACKGROUND: This study investigated the impact of coronary angiography on outcomes of emergency operation in acute type A aortic dissection (ATAAD) patients who were initially misdiagnosed as an acute coronary syndrome. METHODS: From October 2016 to April 2019, 129 patients underwent emergency operation for ATAAD in our institution, including 21 patients (16.3%, coronary angiography group) who received preoperative coronary angiography without knowledge of the ATAAD, and the rest 108 did not (Non-coronary angiography group). Preoperative clinical characteristics, 30-day mortality and postoperative complications were compared. Multivariable logistic regression was performed to confirm the independent prognostic factors for short-term and long-term outcomes. RESULTS: Patients undergoing coronary angiography had higher prevalence of preoperative hypotension or shock (61.9% vs 35.2%, P = 0.022), ischemic changes on electrocardiogram (66.7% vs 37.0%, P = 0.012), platelet inhibition (ADP-induced inhibition 92.0% vs 46.0%, P = 0.001), and coronary involvement (66.7% vs 30.6%, P = 0.002). 30-day mortality was 4.8% versus 9.3% (P = 0.84). Coronary angiography group had more intraoperative bleeding (1900 ml vs 1500 ml, P = 0.013) and chest-tube drainage on the first postoperative day (1040 ml vs 595 ml, P = 0.028). However, preoperative coronary angiography was not independent risk factors for 30-day mortality (OR 0.171, 95%CI 0.013–2.174, P = 0.173) and overall survival (HR 0.407; 95%CI 0.080–2.057; P = 0.277). CONCLUSION: Patients undergoing coronary angiography carried a higher risk of preoperative hemodynamic instability, myocardial ischemia, and perioperative bleeding. However, unintentional coronary angiography did not have a significant impact on short-term and long-term outcomes of emergency surgery in ATAAD. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02821-4.
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spelling pubmed-94002162022-08-25 Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study Peng, Hao Liu, Wei Jian, Kai-Tao Xia, Yu Liu, Jian-Shi Sun, Li-Zhong Mei, Yun-Qing BMC Cardiovasc Disord Research BACKGROUND: This study investigated the impact of coronary angiography on outcomes of emergency operation in acute type A aortic dissection (ATAAD) patients who were initially misdiagnosed as an acute coronary syndrome. METHODS: From October 2016 to April 2019, 129 patients underwent emergency operation for ATAAD in our institution, including 21 patients (16.3%, coronary angiography group) who received preoperative coronary angiography without knowledge of the ATAAD, and the rest 108 did not (Non-coronary angiography group). Preoperative clinical characteristics, 30-day mortality and postoperative complications were compared. Multivariable logistic regression was performed to confirm the independent prognostic factors for short-term and long-term outcomes. RESULTS: Patients undergoing coronary angiography had higher prevalence of preoperative hypotension or shock (61.9% vs 35.2%, P = 0.022), ischemic changes on electrocardiogram (66.7% vs 37.0%, P = 0.012), platelet inhibition (ADP-induced inhibition 92.0% vs 46.0%, P = 0.001), and coronary involvement (66.7% vs 30.6%, P = 0.002). 30-day mortality was 4.8% versus 9.3% (P = 0.84). Coronary angiography group had more intraoperative bleeding (1900 ml vs 1500 ml, P = 0.013) and chest-tube drainage on the first postoperative day (1040 ml vs 595 ml, P = 0.028). However, preoperative coronary angiography was not independent risk factors for 30-day mortality (OR 0.171, 95%CI 0.013–2.174, P = 0.173) and overall survival (HR 0.407; 95%CI 0.080–2.057; P = 0.277). CONCLUSION: Patients undergoing coronary angiography carried a higher risk of preoperative hemodynamic instability, myocardial ischemia, and perioperative bleeding. However, unintentional coronary angiography did not have a significant impact on short-term and long-term outcomes of emergency surgery in ATAAD. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02821-4. BioMed Central 2022-08-24 /pmc/articles/PMC9400216/ /pubmed/36002794 http://dx.doi.org/10.1186/s12872-022-02821-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Peng, Hao
Liu, Wei
Jian, Kai-Tao
Xia, Yu
Liu, Jian-Shi
Sun, Li-Zhong
Mei, Yun-Qing
Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study
title Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study
title_full Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study
title_fullStr Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study
title_full_unstemmed Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study
title_short Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study
title_sort impact of unintentional coronary angiography on outcomes of emergency surgery in acute type a aortic dissection: a retrospective study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400216/
https://www.ncbi.nlm.nih.gov/pubmed/36002794
http://dx.doi.org/10.1186/s12872-022-02821-4
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