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Electrophilic Reagents for the Direct Incorporation of Uncommon SCF(2)CF(2)H and SCF(2)CF(3) Motifs

[Image: see text] The introduction of fluoroalkylthioether groups has attracted the attention of the drug-discovery community given the special physicochemical and pharmacokinetic features they confer to bioactive compounds, yet these are often limited to standard SCF(3) and SCF(2)H moieties. Herein...

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Detalles Bibliográficos
Autores principales: Mestre, Jordi, Bernús, Miguel, Castillón, Sergio, Boutureira, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400389/
https://www.ncbi.nlm.nih.gov/pubmed/35944166
http://dx.doi.org/10.1021/acs.joc.2c01038