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Electrophilic Reagents for the Direct Incorporation of Uncommon SCF(2)CF(2)H and SCF(2)CF(3) Motifs
[Image: see text] The introduction of fluoroalkylthioether groups has attracted the attention of the drug-discovery community given the special physicochemical and pharmacokinetic features they confer to bioactive compounds, yet these are often limited to standard SCF(3) and SCF(2)H moieties. Herein...
Autores principales: | Mestre, Jordi, Bernús, Miguel, Castillón, Sergio, Boutureira, Omar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400389/ https://www.ncbi.nlm.nih.gov/pubmed/35944166 http://dx.doi.org/10.1021/acs.joc.2c01038 |
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