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Immunogenicity of Reduced-Dose Monovalent Type 2 Oral Poliovirus Vaccine in Mocuba, Mozambique

BACKGROUND: The monovalent type 2 oral poliovirus vaccine (mOPV2) stockpile is low. One potential strategy to stretch the existing mOPV2 supply is to administer a reduced dose: 1 drop instead of 2. METHODS: We conducted a randomized, controlled, open-label, noninferiority trial (10% margin) to compa...

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Detalles Bibliográficos
Autores principales:	de Deus, Nilsa, Capitine, Igor Paulo Ubisse, Bauhofer, Adilson Fernando Loforte, Marques, Selma, Cassocera, Marta, Chissaque, Assucênio, Bero, Diocreciano Matias, Langa, José Paulo, Padama, Fernando Manuel, Jeyaseelan, Visalakshi, Oberste, M Steven, Estivariz, Concepcion F, Verma, Harish, Jani, Ilesh, Mach, Ondrej, Sutter, Roland W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400415/ https://www.ncbi.nlm.nih.gov/pubmed/33180924 http://dx.doi.org/10.1093/infdis/jiaa704

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