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Treatment of Skin Tumors with Intratumoral Interleukin 12 Gene Electrotransfer in the Head and Neck Region: A First-in-human Clinical Trial Protocol

BACKGROUND: Immune therapies are currently under intensive investigation providing in many cases excellent responses in different tumors. Other possible approach for immunotherapy is a targeted intratumoral delivery of interleukin 12 (IL-12), a cytokine with anti-tumor effectiveness. Due to its immu...

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Detalles Bibliográficos
Autores principales: Groselj, Ales, Bosnjak, Masa, Jesenko, Tanja, Cemazar, Maja, Markelc, Bostjan, Strojan, Primoz, Sersa, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400442/
https://www.ncbi.nlm.nih.gov/pubmed/35535423
http://dx.doi.org/10.2478/raon-2022-0021