Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry

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Understanding broadly neutralizing sarbecovirus antibody responses is key to developing countermeasures against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and future zoonotic sarbecoviruses. We describe the isolation and characterization of a human monoclonal antibody, des...

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Detalles Bibliográficos
Autores principales: Park, Young-Jun, De Marco, Anna, Starr, Tyler N., Liu, Zhuoming, Pinto, Dora, Walls, Alexandra C., Zatta, Fabrizia, Zepeda, Samantha K., Bowen, John E., Sprouse, Kaitlin R., Joshi, Anshu, Giurdanella, Martina, Guarino, Barbara, Noack, Julia, Abdelnabi, Rana, Foo, Shi-Yan Caroline, Rosen, Laura E., Lempp, Florian A., Benigni, Fabio, Snell, Gyorgy, Neyts, Johan, Whelan, Sean P. J., Virgin, Herbert W., Bloom, Jesse D., Corti, Davide, Pizzuto, Matteo Samuele, Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400459/
https://www.ncbi.nlm.nih.gov/pubmed/34990214
http://dx.doi.org/10.1126/science.abm8143

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