Immune Escape Adaptive Mutations in Hemagglutinin Are Responsible for the Antigenic Drift of Eurasian Avian-Like H1N1 Swine Influenza Viruses

The continuous antigenic variation of influenza A viruses remains a major hurdle for vaccine selection; however, the molecular determinants and mechanisms of antigenic change remain largely unknown. In this study, two escape mutants were generated by serial passages of the Eurasian avian-like H1N1 s...

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Detalles Bibliográficos
Autores principales: Xu, Chengzhi, Zhang, Naixin, Yang, Yuying, Liang, Wenhua, Zhang, Yaping, Wang, Jingfei, Suzuki, Yasuo, Wu, Yunpu, Chen, Yan, Yang, Huanliang, Qiao, Chuanling, Chen, Hualan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Genetic Diversity and Evolution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400474/
https://www.ncbi.nlm.nih.gov/pubmed/35916512
http://dx.doi.org/10.1128/jvi.00971-22

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