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A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection

Ancestral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lacks the intrinsic ability to bind to the mouse ACE2 receptor, and therefore establishment of SARS-CoV-2 mouse models has been limited to the use of mouse-adapted viruses or genetically modified mice. Interestingly, some of the...

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Detalles Bibliográficos
Autores principales:	Abdelnabi, Rana, Foo, Caroline S., Kaptein, Suzanne J. F., Boudewijns, Robbert, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Weynand, Birgit, Neyts, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Vaccines and Antiviral Agents
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400483/ https://www.ncbi.nlm.nih.gov/pubmed/35924921 http://dx.doi.org/10.1128/jvi.00758-22

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