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Interaction with TopBP1 Is Required for Human Papillomavirus 16 E2 Plasmid Segregation/Retention Function during Mitosis

Human papillomavirus 16 (HPV16) E2 is a DNA-binding protein that regulates transcription, replication and potentially, segregation of the HPV16 genome during the viral life cycle. In the segregation model, E2 simultaneously binds to viral and host chromatin, acting as a bridge to ensure that viral g...

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Detalles Bibliográficos
Autores principales:	Prabhakar, Apurva T., James, Claire D., Das, Dipon, Fontan, Christian T., Otoa, Raymonde, Wang, Xu, Bristol, Molly L., Morgan, Iain M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400484/ https://www.ncbi.nlm.nih.gov/pubmed/35880889 http://dx.doi.org/10.1128/jvi.00830-22

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