Switching from ultrafast electron transfer to proton transfer in excited drug–protein complexes upon biotransformation

Photosensitization by drugs is directly related with the excited species and the photoinduced processes arising from interaction with UVA light. In this context, the ability of gefitinib (GFT), a tyrosine kinase inhibitor (TKI) used for the treatment of a variety of cancers, to induce phototoxicity...

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Detalles Bibliográficos
Autores principales: Tamarit, Lorena, El Ouardi, Meryem, Lence, Emilio, Andreu, Inmaculada, González-Bello, Concepción, Vayá, Ignacio, Miranda, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400592/
https://www.ncbi.nlm.nih.gov/pubmed/36091919
http://dx.doi.org/10.1039/d2sc03257k

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