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Inhibitors of the Fanconi anaemia pathway as potential antitumour agents for ovarian cancer

The Fanconi anaemia (FA) pathway is an important mechanism for cellular DNA damage repair, which functions to remove toxic DNA interstrand crosslinks. This is particularly relevant in the context of ovarian and other cancers which rely extensively on interstrand cross-link generating platinum chemot...

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Detalles Bibliográficos
Autores principales: Taylor, Sarah J, Arends, Mark J, Langdon, Simon P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400734/
https://www.ncbi.nlm.nih.gov/pubmed/36046263
http://dx.doi.org/10.37349/etat.2020.00003