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Inhibitors of the Fanconi anaemia pathway as potential antitumour agents for ovarian cancer
The Fanconi anaemia (FA) pathway is an important mechanism for cellular DNA damage repair, which functions to remove toxic DNA interstrand crosslinks. This is particularly relevant in the context of ovarian and other cancers which rely extensively on interstrand cross-link generating platinum chemot...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Open Exploration
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400734/ https://www.ncbi.nlm.nih.gov/pubmed/36046263 http://dx.doi.org/10.37349/etat.2020.00003 |