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Selective Stepwise Arylation of Unprotected Peptides by Pt(IV) Complexes

LPt(IV)F(Aryl) complexes bearing a bulky bidentate 2‐[bis(adamant‐1‐yl)phosphino]phenoxide ligand (L) demonstrate excellent reactivity and selectivity in the arylation of X−H (X=S, N) bonds of amino acid residues in unprotected peptides under mild, including aqueous, conditions. Stepwise addition of...

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Detalles Bibliográficos
Autores principales: Lin, Xiaoxi, Haimov, Elvira, Redko, Boris, Vigalok, Arkadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400855/
https://www.ncbi.nlm.nih.gov/pubmed/35536102
http://dx.doi.org/10.1002/anie.202205368

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