Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold

Benzoxazole scaffolds feature prominently in diverse synthetic and natural product‐derived pharmaceuticals. Our understanding of their bacterial biosynthesis is, however, limited to ortho‐substituted heterocycles from actinomycetes. We report an overlooked biosynthetic pathway in anaerobic bacteria...

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Detalles Bibliográficos
Autores principales: Horch, Therese, Molloy, Evelyn M., Bredy, Florian, Haensch, Veit G., Scherlach, Kirstin, Dunbar, Kyle L., Franke, Jonathan, Hertweck, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400959/
https://www.ncbi.nlm.nih.gov/pubmed/35656913
http://dx.doi.org/10.1002/anie.202205409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400959/
https://www.ncbi.nlm.nih.gov/pubmed/35656913
http://dx.doi.org/10.1002/anie.202205409

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