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Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold
Benzoxazole scaffolds feature prominently in diverse synthetic and natural product‐derived pharmaceuticals. Our understanding of their bacterial biosynthesis is, however, limited to ortho‐substituted heterocycles from actinomycetes. We report an overlooked biosynthetic pathway in anaerobic bacteria...
Autores principales: | Horch, Therese, Molloy, Evelyn M., Bredy, Florian, Haensch, Veit G., Scherlach, Kirstin, Dunbar, Kyle L., Franke, Jonathan, Hertweck, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400959/ https://www.ncbi.nlm.nih.gov/pubmed/35656913 http://dx.doi.org/10.1002/anie.202205409 |
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