Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes

The para‐selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF(2) is reported, with Et(3)N ⋅ 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set‐up, easy scalability and affords a broad...

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Detalles Bibliográficos
Autores principales: Berger, Michael, Lenhard, Marola S., Waldvogel, Siegfried R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401020/
https://www.ncbi.nlm.nih.gov/pubmed/35510825
http://dx.doi.org/10.1002/chem.202201029
Descripción
Sumario:The para‐selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF(2) is reported, with Et(3)N ⋅ 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set‐up, easy scalability and affords a broad variety of fluorinated anilides from easily accessible anilides in good yields up to 86 %.

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